Which Lash Serums contain Prostaglandins (and which Don’t)

If you’re in the market for a lash serums, then you have probably observed that some of them contain prostaglandins, while others don’t. Prostaglandins is an ingredient, which is known for its impressive lash enhancing properties. Although helpful, prostaglandins serums can have certain negative side effects, some of which are long-lasting.

But the peptides-based serums offer a fantastic substitute with a lower risk of negative effects. Prostaglandins are naturally occurring substances that can help to nourish and protect your lashes from daily wear and tear, as well as promote healthy growth in the follicles.

Nowadays, leading beauty companies have started incorporating this beneficial compound into their lash serums. In this blog post, we’ll explore why it matters and why it’s so beneficial, as well as provide an overview of some popular lash serums containing prostaglandins. In this manner, you can select the item that is ideal for you.

Why it Matters

The only eyelash growth serum on the market with FDA approval is Latisse. A prostaglandin called bimatoprost serves as the active component. Now, we know that Latisse is efficient at lengthening your eyelashes because of the various clinical studies that were conducted, but we also know that it may have negative effects.

Therefore, the same adverse effects apply to any other eyelash serum that contains a prostaglandin analogue molecule.

The following are the most frequent negative effects of prostaglandin lash serums:

  • Dryness,
  • Darkening of the skin around the eye,
  • Eye Inflammation,
  • Itchy eyes,
  • Fat atrophy around the eye,
  • Darkening of the eye color,
  • Swelling of the retina,

Prostaglandin-based lash growth serums, with the exception of Latisse, are sold as cosmetics and are not subject to FDA approval like a pharmaceutical would be. This indicates that the businesses are exempt from the substantial safety testing required for a medicine.

That’s a major problem.

Since these items contain an active substance, they really ought to be handled like medications. It is crucial to consider whether you are OK with any possible adverse effects before using a prostaglandin analogue eyelash growth serum.

Lash Serums with Prostaglandins

Eyelash SerumContains Prostaglandin?Active Ingredient
GrandeLASHYesIsopropyl Cloprostenate
R + F Lash BoostYesIsopropyl Cloprostenate
RevitaLashYesDechloro Dihydroxy Difluoro Ethylcloprostenolamide
neuLASHYesIsopropyl Cloprostenate
RapidLashYesIsopropyl Cloprostenate
Babe LashYesIsopropyl Cloprostenate

There are more prostaglandin analogues besides bimatoprost. The following examples of synthetic prostaglandins can be found in the ingredient list:

  • Isopropyl cloprostenate,
  • Isopropyl phenylhydroxypentene,
  • Dihydroxy cyclopentyl heptane,
  • Dechloro dihydroxy difluoro ethylcloprostenolamide,

So, when reading the label, it’s crucial to be aware of these other names.

Lash Serums without Prostaglandins

The majority of these serums are peptide-based, which means they encourage the development of keratin to encourage the growth of your own lashes. The majority of these serums will help maintain the three phases of your eyelashes’ growth cycle:

  • Anagen (active growth phase)
  • Catagen (transition phase)
  • Telogen (resting phase)

Yes, they are supported by fewer clinical studies. They are considerably less likely to have negative effects, though. You must ultimately decide and accept the risks associated with your choice.


Do all Lash Serums contain Prostaglandins?

No, not all lash serums contain prostaglandins. Some of them are peptide-based and have other active ingredients different from prostaglandins.

Are prostaglandin lash serums safe?

Yes, prostaglandin-based lash growth serums are generally safe, but they may have certain side effects on some users, such as dryness and darkening of the skin around the eyes. It is therefore important to be aware of what is in the ingredients list and also consult your doctor before using them.  

Does Vegamour Lash serum contain Prostaglandins?

No, Vegamour GRO lash serum does not contain prostaglandins. It is peptide-based and has other active ingredients different from prostaglandins.

What are Prostaglandins based Eyelash serums?

Prostaglandin based eyelash growth serums are products that contain a prostaglandin analogue molecule, such as bimatoprost, as their active ingredient. These molecules stimulate hair growth by regulating the eyelash cycle. The only prostaglandin based serum with FDA approval is Latisse, but there are other products that contain prostaglandin analogues available over the counter. These should be handled with care and caution should be taken when using them due to their potential side effects.


It is important to know the ingredients in Lash serums and whether they contain Prostaglandins or not. While Lash Serums with prostaglandins are generally safe and have been approved by the FDA, they may also have certain serious side effects.

Therefore, it is important to be aware of what is in the ingredients list and also consult your doctor before using the product. Additionally, there are Lash Serums which don’t contain prostaglandins and are peptide-based. It is ultimately up to you to decide which serum suits you best and accept the risks associated with your choice.

It is important to use the lash serum safely and to be well-informed before using them. With a bit of research and the right product, you can have the lashes of your dreams! Good luck on your lash journey!

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